Although CO2 laser processing equipment has become more popular in recent years, laser is a new tool after all, and laser processing technology is also different from traditional processing methods. Therefore, the industry has encountered various problems in the process of introducing and using CO2 lasers. Such problems have caused a lot of trouble for many manufacturers. This article analyzes the application status and evolution of CO2 lasers in different fields, and puts forward some problems that are often faced in the process of using CO2 lasers. According to the power level of CO2 lasers, the application status and evolution in various industries are explained. Situation, enumerate and analyze the main problems faced by CO2 laser users, and finally put forward a prospect for the future of CO2 laser applications. CO2 laser is a relatively important gas laser. This is because it has some prominent advantages: First, it has relatively large power and relatively high energy conversion efficiency. A general closed-tube CO2 laser can have a continuous output power of several tens of watts, which is far more than other gas lasers, and a lateral flow electrically excited CO2 laser can have a continuous output of hundreds of thousands of watts. In addition, the lateral atmospheric pressure CO2 laser has reached a higher level in energy and power from the pulse output, which is comparable to solid-state lasers. The energy conversion efficiency of CO2 lasers can reach 30-40%, which also exceeds that of general gas lasers. Secondly, it uses the transition between the vibration-rotational energy levels of the CO2 molecule. It has a relatively rich spectrum, and there are dozens of spectrum lines in the laser output around 10 microns. The high-pressure CO2 laser discovered in recent years can even achieve a continuously tunable output from 9 to 10 microns. Third, its output band is exactly the atmospheric window (that is, the transparency of the atmosphere to this wavelength is higher). In addition, it also has the advantages of high optical quality of the output beam, good coherence, narrow line width, and stable operation. Therefore, it has many applications in the national economy and national defense, such as processing (welding, cutting, drilling, etc.), communications, radar, chemical analysis, laser-induced chemical reactions, and surgical operations. Carbon dioxide laser is a kind of laser with higher continuous output power. It developed earlier and commercial products are more mature. It is widely used in materials processing, medical use, military weapons, environmental measurement and other fields. Regarding the development and application of lasers, CO2 lasers were produced and applied earlier and more frequently. As early as the late 1970s, CO2 lasers were directly imported from abroad for industrial processing and medical applications. Since the late 1980s, CO2 lasers have been widely introduced and used in the field of material processing. (For the editing details of High Energy Laser Equipment Manufacturing Co., Ltd., please refer to http://www.gnlaser.com/?fnew/i577)